Causes, Forms and a Regenerative Approach
Acne is a chronic inflammatory skin condition associated with hormonal imbalance, increased sebum production and impaired tissue regeneration. In some cases, it involves deep inflammatory lesions and scarring.
The condition presents across a broad spectrum of skin changes. Superficial comedones and deep inflammatory processes may be observed. Certain forms carry a high risk of permanent scarring. Several interconnected pathological mechanisms underlie its development.
How Acne Develops
During puberty, acne results from a temporary hormonal imbalance. A relative increase in male sex hormones is observed. This leads to increased activity of the sebaceous glands and blockage of hair follicles. The process is transient. In some individuals, it resolves without residual changes.
When acne persists after puberty or appears in adulthood, a sustaining factor is usually present. Most often, this involves chronic inflammation, hormonal disturbance, or a combination of several processes. The skin manifestations reflect a deeper underlying imbalance.
Forms of Acne
Non-inflammatory acne (comedones)
Non-inflammatory forms present as comedones. These are blocked hair follicles without active infection.
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Whiteheads – represent closed comedones with superficial accumulation of sebum.
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Blackheads – are open comedones. The dark coloration results from oxidation of the contents rather than external contamination.
Inflammatory acne
Inflammatory forms include papules, pustules, nodules and cysts.
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Papules – are superficial red inflammatory lesions.
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Pustules –represent deeper lesions containing purulent material.
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Nodules –are deep and painful lesions with involvement of infectious agents.
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Cysts – are the most severe form. They extend to significant depth and carry a high risk of scarring.
Why Acne Persists
Acne rarely has a single cause. Genetic predisposition, hormonal fluctuations and chronic inflammation play a central role. Impaired local blood supply, reduced tissue oxygenation and mitochondrial dysfunction further contribute to persistence. Secondary bacterial or fungal infections are frequently present. In some patients, tissue regenerative capacity is reduced. Systemic conditions and long-term use of certain medications may also influence disease course.
The Regenics Medical Approach
At Regenics Medical, a comprehensive assessment of the affected tissues and the patient’s overall condition is performed. Apart from the physiological hormonal changes of puberty, particular attention is given to hormonal balance. When concomitant conditions are present, these are carefully evaluated, and collaboration with specialists in the relevant fields is undertaken.
Our tissue restorative work focuses primarily on controlling inflammatory processes and preventing or addressing their consequences. In the most severe cases, this includes the management of scarring.
Following this assessment, a personalised plan for skin tissue restoration is developed.
Gentle Therapies for Skin Restoration
Depending on the underlying cause of acne, the depth of the affected tissues and the extent of the involved areas, Regenics Medical technologies are applied to achieve effective control of inflammation while simultaneously activating the body’s own regenerative resources.
Technologies based on autologous growth factors (Endoret™), light-based therapy using chromophore substances that transmit photon energy (Fletech™), and cold atmospheric plasma (PlasmaOne™) are employed.
In cases of inflammatory acne, treatment typically begins with physico-chemical elimination of pathogenic bacteria and fungi without the use of antibiotics, while simultaneously enhancing local blood circulation through PlasmaOne™.
This is followed by the application of precisely focused LED light delivered through a specialised photoconverter gel. This significantly enhances antibacterial and antifungal effects, as well as the anti-inflammatory action of light photons, through Fletech™ technology.
In parallel with these methods, autologous growth factors (Endoret™) are used in various formulations to modulate the local immune system and restore tissue balance. At the same time, tissue-resident stem cells are activated and tissue regeneration is enhanced. A specially prepared serum derived from the patient’s plasma (Endoret™) is also used. It has antibacterial and antifungal properties, while the contained growth factors promote tissue repair. This serum is suitable for home use. In cases where scars have already formed, they are treated with a tissue-restorative filler rich in autologous growth factors, produced entirely from the patient’s own plasma (Endoret™).
What Distinguishes the Regenics Medical Approach
- Minimally invasive and tissue-sparing procedures.
- Elimination and prevention of infections.
- Improvement of local blood circulation.
- Balancing of the local immune response.
- Support of cellular and tissue regeneration.
- Alignment with the physiological principles of the human body.
- Activation of stem cells and regenerative processes.
- Enhancement of cellular energy production.
- Prevention of scar formation or reduction of existing scars.
- Improvement of skin structure and elasticity.
- Short recovery period of up to two to three days.
- Absence of serious side effects.
Treatment Duration and Recovery
- Depending on the treated areas, a single procedure lasts between 45 minutes and 1.5 hours. Multiple techniques are often combined to enhance the therapeutic effect.
- Visible improvement typically appears within approximately one week. Resolution of active acne may take up to one month. Significant reduction or disappearance of scarring usually requires two to three months.
Frequently Asked Questions (FAQ)
What is the main cause of acne?
The most common cause is hormonal imbalance. It leads to increased sebum production and blockage of hair follicles. In adulthood, chronic inflammation is often an additional contributing factor.
Is it normal for acne to persist after puberty?
Yes. In such cases, a sustaining factor is usually present. Most often, this involves a hormonal or inflammatory disturbance.
What is the difference between whiteheads and blackheads?
Whiteheads are closed comedones. Blackheads are open comedones. The dark coloration results from oxidation.
Can acne cause scarring?
Yes. The risk is highest in deep inflammatory forms and when treatment or control is delayed.
Are antibiotics used?
No. The approach does not involve antibiotic therapy. Control is achieved through physico-chemical and regenerative methods.